Protein Details: Potassium voltage-gated channel subfamily S member 1
Protein ID
ICDB_Pro_0043
Protein Name
Potassium voltage-gated channel subfamily S member 1
Gene Name
KCNS1
Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Length
526 amino acids
AlphaFoldDB
AF-A4K2R3-F1-model_v4.pdb
Function
Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2
Sequence
MLMLLVRGTHYENLRSKVVLPTPLAGRSTETFVSEFPGPDTGIRWRRSDEALRVNVGGVRRQLSARALARFPGTRLGRLHAAASEEQARRLCDDYDEAAREFYFDRHPGFFLSLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRLTQPHAWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGGKEFGHLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKEEDVGFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVRNSNHREFEDLLSSVDGVSEASLETSGETSQEGRSADLESQAPSEPPHPQRY
PDB Structures
Ligand Binding
Binding Site
Disease
Location
DOI ID
10.1101/gr.6004607